OfficePools allows for your Football Pick'em pool format to be based on either Straight-Up or Spread. This article clarifies the difference between the 2 types.

Straight-Up: In this Pick'em type, the poolie makes their predictions based on the actual outcomes of the games. For example, if the poolie predicts that Seattle will beat San Francisco. They are correct as long as Seattle wins the game in real life.

Spread: In this Pick'em type, the poolies makes their predictions based on the spread outcomes of the games. For example, if Seattle is favoured by 4.5 points over San Francisco:

The poolie has the option of either predicting that Seattle will win by at least 5 points by selecting SEA -4.5

OR

predicting that Seattle will NOT win by at least 5 points (4 points or less) OR San Francisco will win outright. They do this by selecting SF +4.5.